The actual paper is here [1]. And it’s not quite as conclusive in mammals yet. But it sounds like there is a clinical trial to actually study the supplement, which is a welcome thing in the anti-aging world. I’m happy to read that this work came out of the Buck Institute in Novato, which is a solid research institution. It’s also a beautiful campus.
Disclaimer: I was there for a short stint as a postdoc a while back and not connected to this paper at all.
That articles says "Alpha-ketoglutarate is a key metabolite in the tricarboxylic acid (TCA) cycle, and its levels change upon fasting, exercise, and aging."
But there is no citation for this statement. Any idea where to read about how these levels change naturally?
Disclaimer: I was there for a short stint as a postdoc a while back and not connected to this paper at all.
[1] https://doi.org/10.1016/j.cmet.2020.08.004